Program

Friday, 16 June 2023

08:00 – 09:00	Registration
09:00 – 09:10	Opening of the meeting Petr Svoboda, Chairman of the Council of the Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, CZ
Chair: Scott Keeney
09:10 – 09:50	Germline mutagenesis at double-strand break hotspots Maria Jasin, Memorial Sloan Kettering Cancer Center, New York, US
09:50 – 10:30	Secret of safe sex: controlling meiotic DNA breaks Attila Toth, Technical University of Dresden, Dresden, DE
10:30 – 11:00	Coffee break
Chair: Jiří Forejt
11:00 – 11:40	Meiotic peculiarities of the germline-restricted chromosome of songbirds Radka Reifová, Charles University, Prague, CZ
11:40 – 12:20	Meiotic role of m6A RNA methylation David Homolka, University of Geneva, Geneva, CH
12:20 – 13:00	Cohesin and Chromosome Segregation in Oocytes: a Goldilocks scenario Neil Hunter, HHMI, University of California, Davis, US
13:00 – 14:30	Lunch
Chair: Maria Jasin
14:30 – 15:10	Assembly of the meiotic double-strand break machinery Scott Keeney, HHMI, Memorial Sloan Kettering Cancer Center, New York, US
15:10 – 15:50	FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in meiotic DNA replication and recombination Akira Shinohara, Osaka University, Osaka, JP
15:50 – 16:30	Super-resolution view on chromosome pairing and DSB repair in mouse meiosis Willy Baarends, Erasmus Medical Center, Rotterdam, NL
16:30 – 17:00	Coffee break
Chair: Attila Toth
17:00 – 17:40	PRDM9, short- and long-term consequences of a sophisticated tool to specify the sites of meiotic recombination Bernard de Massy, Institute of Human Genetics, CNRS, Montpellier, FR
17:40 – 18:20	Pairing and synapsis of evolutionarily diverged homologs: Chromosomal hybrid sterility revisited Jiří Forejt, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, CZ
18:30	POSTER SESSION & glass of wine
19:00 – 21:00	Dinner

Each lecture will be followed by a 10-minute discussion (included in the total lecture time).